Compile Data Set for Download or QSAR
maximum 50k data
Found 326 of ic50 data for polymerid = 1171
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530183(Preparation of 4-[(2S)-2-(cyanomethyl)-2-methyl-bu...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530189(Preparation of 4-(3-fluoro-2,2-dimethyl-butanoyl)-...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530189(Preparation of 4-(3-fluoro-2,2-dimethyl-butanoyl)-...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530191(Preparation of 4-[(3S)-3-fluoro-2,2-dimethyl-butan...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530197(Preparation of 4-[2-(3-chlorocyclobutyl)-2-methyl-...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530198(Preparation of 4-[2-methyl-2-[3-(trifluoromethoxy)...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530199(Preparation of 4-[2-[(3S)-1-(5-fluoropyrimidin-2-y...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530203(Preparation of 4-[(4R)-3,3-difluoro-1-(5-fluoropyr...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530206(Preparation of 4-[1-(3,5-difluoro-6-methoxy-2-pyri...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530206(Preparation of 4-[1-(3,5-difluoro-6-methoxy-2-pyri...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530208(Preparation of 4-[1-(3,5-difluoro-6-methoxy-2-pyri...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530213(Preparation of 4-[4-fluoro-1-(5-fluoro-[1,2,4]tria...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530214(Preparation of 4-[(4S)-3,3,4-trifluoro-1-(5-fluoro...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530216(Preparation of 4-[(4R)-3,3-difluoro-4-methyl-1-pyr...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530218(Preparation of 4-[(3S,4R)-3-fluoro-1-(5-fluoropyri...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530218(Preparation of 4-[(3S,4R)-3-fluoro-1-(5-fluoropyri...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530220(Preparation of 4-[(3R,4R)-3-fluoro-1-([1,2,4]triaz...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530222(Preparation of 4-[(3R,4R)-3-fluoro-1-(3-fluoropyra...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530224(Preparation of 4-[(3R,4R)-3-fluoro-1-(5-fluoropyri...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530226(Preparation of 4-[(4R)-3,3-difluoro-1-(5-fluoropyr...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530069(4-(2,2,3- trimethylbutanoyl)- 3,5-dihydro-2H- pyri...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530071(4-[3-fluoro-2- (fluoromethyl)-2- methyl-propanoyl]...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530072(4-(2-methyl-2- methylsulfanyl- propanoyl)-3,5- dih...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530075(4-(2-ethyl-2- methyl-butanoyl)- 3,5-dihydro-2H- py...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530077(4-(2-methoxy-2- methyl-butanoyl)- 3,5-dihydro-2H- ...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530079(4-[1-(5- fluoropyrimidin-2- yl)piperidine-4- carbo...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530080((9-fluoro-3,5- dihydro-2H- pyrido[3,4- f][1,4]oxaz...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530081(4-(4-fluoro-1- pyrimidin-2-yl- piperidine-4- carbo...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530082(4-(2-chloro-2- methyl-propanoyl)- 3,5-dihydro-2H- ...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530085(4-[4-fluoro-1-(5- fluoropyrimidin-2- yl)piperidine...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530088(4-[1-(5- chloropyrimidin-2- yl)-4-fluoro- piperidi...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530099(4-(2,2- dimethylpropanoyl)- 3,5-dihydro-2H- pyrido...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530101(4-[4-chloro-1-(5- fluoropyrimidin-2- yl)piperidine...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530102(4-[1-(4-ethoxy-5- fluoro-pyrimidin-2- yl)-4-fluoro...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530106(4-[1-(5- fluoropyrimidin-2- yl)piperidine-4- carbo...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530107(4-[4-fluoro-1-(5- fluoro-4-methyl- pyrimidin-2- yl...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530108(4-[1-(5- fluoropyrimidin-2- yl)-4-methoxy- piperid...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530110(4-[1-(5- fluoropyrimidin-2- yl)-3-methyl- piperidi...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530111(4-[4-fluoro-1-(5- fluoro-2- pyridyl)piperidine- 4-...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530114(4-[4-fluoro-1-(5- fluoro-4-methoxy- pyrimidin-2- y...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530115(4-[1-(3,5-difluoro- 2-pyridyl)-4-fluoro- piperidin...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530117(4-[1-(5-fluoro-4- methoxy-pyrimidin- 2-yl)-4-metho...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530122(4-[4-fluoro-1-(3- isoquinolyl)piperidine- 4-carbon...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530123(4-[4-fluoro-1-(2- quinolyl)piperidine- 4-carbonyl]...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530124(4-[1-(4- cyclopropyl-5- fluoro-pyrimidin-2- yl)-4-...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530125(4-[1-(2-chloro-5- fluoro-pyrimidin-4- yl)-4-fluoro...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530128(4-[4-fluoro-1- ([1,2,4]triazolo[1,5- a]pyrazin-8- ...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530135(4-(1-(5- chloropyrimidin-2- yl)-3,3-difluoro-4- me...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530137(4-[3,3-difluoro-1- [5-fluoro-4-(2- methoxyethoxy) ...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Homo sapiens (Human))
Denali Therapeutics

US Patent
LigandPNGBDBM530142(4-[3,3-difluoro-4- methyl-1- ([1,2,4]triazolo[1,5-...)
Affinity DataIC50: <100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 326 total ) | Next | Last >>
Jump to: